Clinical use
Use this calculator for alcoholic hepatitis severity and steroid treatment decision in thehepatology workflow. It is decision support and should be interpreted with the patient context, local protocols, and clinician judgment.
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Hepatology
Maddrey's Discriminant Function Calculator
Alcoholic hepatitis severity and steroid treatment decision
Calculate Maddrey DF
Interpretation
DF ≥32: severe alcoholic hepatitis — consider prednisolone 40 mg/day for 28 days. Assess response with Lille score at day 7.
Required inputs
- Pt
- Control Pt
- Bilirubin
Evidence and limitations
This page cites 1 published reference. Confirm units and inclusion criteria before applying the output; calculators do not replace assessment, escalation, or local policy.
References
- Maddrey WC et al. Gastroenterology 1978;75:193-199
Frequently asked questions
What is the Maddrey's Discriminant Function?
Maddrey's Discriminant Function is a clinical calculator used for Alcoholic hepatitis severity and steroid treatment decision.
How do I interpret the Maddrey's Discriminant Function?
DF ≥32: severe alcoholic hepatitis — consider prednisolone 40 mg/day for 28 days. Assess response with Lille score at day 7.
What inputs are required for the Maddrey's Discriminant Function?
Required inputs include Pt, Control Pt, Bilirubin.
What is the evidence behind the Maddrey's Discriminant Function?
The Maddrey's Discriminant Function page cites Maddrey WC et al. Gastroenterology 1978;75:193-199.
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