Rheumatology

SLEDAI-2K Calculator

SLE Disease Activity Index

Clinical use

Use this calculator for sle disease activity index in therheumatology workflow. It is decision support and should be interpreted with the patient context, local protocols, and clinician judgment.

Interpretation

Total 0-105. 0 = inactive. 1-5 mild. 6-10 moderate. 11-19 high. ≥20 very high activity. Flare = ≥3 increase from baseline. Used for treatment escalation and trial endpoints.

Required inputs

Seizure
Psychosis
Organic Brain Syndrome
Visual Disturbance
Cranial Nerve Disorder
Lupus Headache
Cva
Vasculitis
Arthritis
Myositis
Urinary Casts
Hematuria
Proteinuria
Pyuria
Rash
Alopecia
Mucous Membrane Ulcers
Pleurisy
Pericarditis
Low Complement
Increased Dna Binding
Fever
Thrombocytopenia
Leukopenia

Evidence and limitations

This page cites 1 published reference. Confirm units and inclusion criteria before applying the output; calculators do not replace assessment, escalation, or local policy.

References

Bombardier C et al. Arthritis Rheum 1992;35:630-640

Frequently asked questions

What is the SLEDAI-2K?

SLEDAI-2K is a clinical calculator used for SLE Disease Activity Index.

How do I interpret the SLEDAI-2K?

Total 0-105. 0 = inactive. 1-5 mild. 6-10 moderate. 11-19 high. ≥20 very high activity. Flare = ≥3 increase from baseline. Used for treatment escalation and trial endpoints.

What inputs are required for the SLEDAI-2K?

Required inputs include Seizure, Psychosis, Organic Brain Syndrome, Visual Disturbance, Cranial Nerve Disorder, Lupus Headache, Cva, Vasculitis, Arthritis, Myositis, Urinary Casts, Hematuria, Proteinuria, Pyuria, Rash, Alopecia, Mucous Membrane Ulcers, Pleurisy, Pericarditis, Low Complement, Increased Dna Binding, Fever, Thrombocytopenia, Leukopenia.