Clinical use
Use this calculator for unmeasured anions for metabolic acidosis workup in theelectrolytes workflow. It is decision support and should be interpreted with the patient context, local protocols, and clinician judgment.
Calculate AG
Interpretation
Normal: 8-12 mEq/L (albumin-corrected). Elevated: MUDPILES differential (Methanol, Uremia, DKA, Propylene glycol, INH/Iron, Lactic acidosis, Ethylene glycol, Salicylates).
Required inputs
- Sodium
- Chloride
- Bicarbonate
Optional: Albumin
Evidence and limitations
This page cites 1 published reference. Confirm units and inclusion criteria before applying the output; calculators do not replace assessment, escalation, or local policy.
References
- Kraut JA, Madias NE. Clin J Am Soc Nephrol 2007;2:162-174
Frequently asked questions
What is the Anion Gap?
Anion Gap is a clinical calculator used for Unmeasured anions for metabolic acidosis workup.
How do I interpret the Anion Gap?
Normal: 8-12 mEq/L (albumin-corrected). Elevated: MUDPILES differential (Methanol, Uremia, DKA, Propylene glycol, INH/Iron, Lactic acidosis, Ethylene glycol, Salicylates).
What inputs are required for the Anion Gap?
Required inputs include Sodium, Chloride, Bicarbonate. Optional inputs include Albumin.
What is the evidence behind the Anion Gap?
The Anion Gap page cites Kraut JA, Madias NE. Clin J Am Soc Nephrol 2007;2:162-174.
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