Clinical use
Use this calculator for estimated serum osmolality and osmolar gap in theelectrolytes workflow. It is decision support and should be interpreted with the patient context, local protocols, and clinician judgment.
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Electrolytes
Calculated Serum Osmolality Calculator
Estimated serum osmolality and osmolar gap
Calculate Osm
Interpretation
Normal: 275-295 mOsm/kg. Osmolar gap >10: consider toxic alcohols (methanol, ethylene glycol). Elevated without gap: hypernatremia, hyperglycemia, uremia.
Required inputs
- Sodium
- Glucose
- BUN
Optional: Ethanol
Evidence and limitations
This page cites 1 published reference. Confirm units and inclusion criteria before applying the output; calculators do not replace assessment, escalation, or local policy.
References
- Purssell RA et al. Ann Emerg Med 2001;38:653-659
Frequently asked questions
What is the Calculated Serum Osmolality?
Calculated Serum Osmolality is a clinical calculator used for Estimated serum osmolality and osmolar gap.
How do I interpret the Calculated Serum Osmolality?
Normal: 275-295 mOsm/kg. Osmolar gap >10: consider toxic alcohols (methanol, ethylene glycol). Elevated without gap: hypernatremia, hyperglycemia, uremia.
What inputs are required for the Calculated Serum Osmolality?
Required inputs include Sodium, Glucose, BUN. Optional inputs include Ethanol.
What is the evidence behind the Calculated Serum Osmolality?
The Calculated Serum Osmolality page cites Purssell RA et al. Ann Emerg Med 2001;38:653-659.
Next steps
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